2026
Application of machine learning and artificial intelligence methods in the predictions of absorption, distribution, metabolism, and excretion properties of chemicals
Wei-Chun Chou, Miao Li, Srijit Seal, Zhoumeng Lin
Machine Learning and Artificial Intelligence in Toxicology and Environmental Health. 2026, Pages 61-97
Developing a multi-task quantitative structure-activity relationship (QSAR) model for predicting the toxicity potential of chemicals used in e-cigarette products
Journal of Hazardous Materials. Volume 503, 1 February 2026, 141164
Applications of machine learning and artificial intelligence in toxicology and environmental health
Zhoumeng Lin, Pei-Yu Wu, Wei-Chun Chou
Machine Learning and Artificial Intelligence in Toxicology and Environmental Health. 2026, Pages 1-26
Application of machine learning and artificial intelligence methods in physiologically based pharmacokinetic modeling
Wei-Chun Chou, Miao Li, Zhoumeng Lin
Machine Learning and Artificial Intelligence in Toxicology and Environmental Health. 2026, Pages 99-138
Basics of machine learning and artificial intelligence methods in toxicology and environmental health
Wei-Chun Chou, Weitao Chen, Kunpeng Chen
Machine Learning and Artificial Intelligence in Toxicology and Environmental Health. 2026, Pages 27-59
2025
Transfer learning enables robust prediction of cellular toxicity from environmental micro- and nanoplastics - ScienceDirect
Kunpeng Chen, Keyuan Li, Alexa Canchola, Jinyong Liu, Qing Liu, Wei-Chun Chou
Journal of Hazardous Materials. Volume 496, 15 September 2025, 139353
Advancing non-target analysis of emerging environmental contaminants with machine learning: Current status and future implications
Alexa Canchola, Lillian N. Tran, Wonsik Woo, Linhui Tian, Ying-Hsuan Lin, Wei-Chun Chou
Environment International. Volume 198, April 2025, 109404
A Machine Learning-Based Clustering Analysis to Explore Bisphenol A and Phthalate Exposure from Medical Devices in Infants with Congenital Heart Defects
Development of a physiologically based pharmacokinetic model for flunixin in cattle and swine following dermal exposure
Xue Wu, Qiran Chen, Wei-Chun Chou, Fiona P Maunsell, Lisa A Tell, Ronald E Baynes, Jennifer L Davis, Majid Jaberi-Douraki, Jim E Riviere, Zhoumeng Lin
Toxicological Sciences, Volume 203, Issue 2, February 2025, Pages 181–194
Effects of Serum Insulin and Insulin-Like Growth Factor 1 Levels on the Association between Fetal Growth and Per- and Polyfluoroalkyl Substance Exposure Based on a Nested Case–Control Study
Dan Cai, Shen-Pan Li, Yu-Ting Guo, Wei-Chun Chou, Zeeshan Mohammed, Rong-Liang Qiu, Guocheng Hu, Jianying Qi, Mingzhong Ren, Mingdeng Xiang, Zhenchi Li, Yang Zhou, Jinbo Huang, Minli Kong, Yanqi Xie, Cuilan Tang, Li-Zi Lin, Yunjiang Yu, Guang-Hui Dong, Xiao-Wen Zeng
Development of machine learning-based quantitative structure–activity relationship models for predicting plasma half-lives of drugs in six common food animal species
Pei-Yu Wu, Wei-Chun Chou, Xue Wu, Venkata N Kamineni, Yashas Kuchimanchi, Lisa A Tell, Fiona P Maunsell, Zhoumeng Lin
Toxicological Sciences, Volume 203, Issue 1, January 2025, Pages 52–66
2024
Hepatic injury and ileitis associated with gut microbiota dysbiosis in mice upon F–53B exposure
Shenpan Li, LuYin Wu, HuiXian Zeng, Jing Zhang, ShuangJian Qin, Li-Xia Liang, John Andersson, Wen-Jie Meng, Xing-Yu Chen, Qi-Zhen Wu, Li-Zi Lin, Wei-Chun Chou, Guang-Hui Dong, Xiao-Wen Zeng
Environmental Research 248, 118305
Predicting tissue distribution and tumor delivery of nanoparticles in mice using machine learning models
Kun Mi, Wei-Chun Chou, Qiran Chen, Long Yuan, Venkata N Kamineni, Yashas Kuchimanchi, Chunla He, Nancy A Monteiro-Riviere, Jim E Riviere, Zhoumeng Lin
​Journal of Controlled Release 374, 219-229
Long-term exposure to major constituents of fine particulate matter and neurodegenerative diseases: A population-based survey in the Pearl River Delta Region, China
Qi-Zhen Wu, Hui-Xian Zeng, John Andersson, Anna Oudin, Katja M Kanninen, Mu-Wu Xu, Shuang-Jian Qin, Qing-Guo Zeng, Bin Zhao, Mei Zheng, Nanxiang Jin, Wei-Chun Chou, Pasi Jalava, Guang-Hui Dong, Xiao-Wen Zeng
Journal of Hazardous Materials 470, 134161
Preface to the special issue of Food and Chemical Toxicology on “New approach methodologies and machine learning in food safety and chemical risk assessment: Development of reproducible, open-source, and user-friendly tools for exposure, toxicokinetic, and toxicity assessments in the 21st century”
Zhoumeng Lin, Danilo Basili, Wei-Chun Chou
Food and Chemical Toxicology 190, 114809
LncRNA NR_030777 promotes mitophagy by targeting CDK1-related mitochondrial fission and ATG12 to attenuate paraquat-induced Parkinson's disease
Nengzhou Chen, Hong Hu, Jianping Tang, Fuli Zheng, Zhenkun Guo, Xinpei Lin, Michael Aschner, Wenya Shao, Guangxia Yu, Ping Cai, Wei-Chun Chou, Siying Wu, Huangyuan Li
​Environmental Pollution 349, 123875
Rebuttal to Correspondence on “Fetal Glucocorticoid Mediates the Association between Prenatal Per- and Polyfluoroalkyl Substance Exposure and Neonatal Growth Index: Evidence from a Birth Cohort Study”
Dan Cai, Qing-qing Li, Zeeshan Mohammed, Wei-Chun Chou, Jinbo Huang, Minli Kong, Yanqi Xie, Yunjiang Yu, Guocheng Hu, Jianying Qi, Yang Zhou, Weihong Tan, Lizi Lin, Rongliang Qiu, Guanghui Dong, Xiao-Wen Zeng
Environmental Science & Technology 58 (43), 19568-19569
Physiologically based pharmacokinetic modeling of metal nanoparticles for risk assessment of inhalation exposures: a state-of-the-science expert panel review
CR Kirman, B Kent, J Bigelow, RA Canady, Q Chen, WC Chou, D Li, Z Lin, V Kumar, A Paini, P Poulin, LM Sweeney, SM Hays
Nanotoxicology 18 (6), 527-541